Rosetta is a distributed computing project using the Boinc platform. This platform allows volunteers to download client software which will run on their computer, and depending on settings will run at all time, or while the computer is turned on but not in use to participate in scientific projects. Rosetta@Home is one such project which uses volunteers computers distributed throughout the world, connected via the internet to predict protein structures.
The Rosetta system is used in FoldIt, which has thus far proven to be one of the most accurate methods of protein structure prediction through computer simulation. More information may be found at the Rosetta@Home website.
If you wish to participate in Boinc projects, you may download the software from the official site. Boinc Site
If you feel the Boinc software may be too complicated, or do not wish to spend as long configuring and choosing projects, another great site which offers access to these projects, and an online tool to manage participation is: Grid Republic
FoldIt Users' Perspectives on RosettaEdit
"Rosetta is very bad at ends. I had only one Rosetta puzzle where rebuilds didn't give a bunch of points, and that was one where one end was only a single Amino Acid." LennStar 13:29, 4 June 2009 (UTC)
Other Active Protein Related Boinc ProgramsEdit
A German protein structure prediction project, utilizing a different prediction method.
A project to compare, categorize, and catalog protein structures for publication in their database.
An eclectic project which covers many different fields including protein research.
A project to improve and refine quantum monte carlo calculations.
A project which uses Play Station 3 gaming consoles and Nvidia graphics cards to perform research.
A project to test interactions of proteins to aid in drug research.
A project trying to find solutions to clean hydrogen production by finding efficient biological fuel cells.
A project researching and attempting to create new disease fighting drugs.
A multi-faceted project for the University of Maryland Center of Bioinformatics and Computational Biology to assist them in their research.
Another eclectic project that includes research in docking simulations along with research of protein structure within the brain and nervous system. Other research areas include nano-scale light, nano-scale magnetics, and fusion.