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Puzzle 497

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497 CASP ROLL Puzzle 2b

R0002 in Casp Roll

R0002 in german wiki

The target is a member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. The corresponding UNIPROT accession code is Q6NW40. The structure of the target protein has been solved in complex with its receptor Neogenin (Q92859, residues 853 to 1052), for which experimental structures are available.

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