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In this puzzle, a small piece of protein has two sidechains. A spiky red ball shows that the sidechains are clashing.

One Small Clash (icon)

One Small Clash. Move one of the sidechains to clear the clash.

Madde's "One Small Clash" video

Loci's "One Small Clash" video

Foldit Research's "One Small Clash" video

You can drag the sidechains with the mouse.

Get rid of the clash by clicking and dragging one of the sidechains away from the other.

Technical stuff: this puzzle has only three segments. The orange hydrophobic sidechain on the left is tyrosine. The blue hydrophilic sidechain on right is either glutamate or glutamine, which have the same shape. There's a segment in between the two sidechains, which is glycine. Glycine has no sidechain.

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