Welcome to the Foldit Wiki
Foldit is an online game in which humans try to solve one of the hardest computational problems in biology: protein folding. You don't need to know anything about biology to play the game, although a little background will help. Most of the players of Foldit are not biologists. Read about The Science Behind Foldit.
Visit the official Foldit site for downloads, puzzle and player information, the Foldit developer's blog, and feedback for reporting problems. (Use the feedback page if you're having trouble getting Foldit installed, or if the game crashes.)
- Oldie but goodie: 2013 animated video featuring the Contender's mimi and Renton Innes. (Someone's Kiwi accent is deemed to require subtitles.)
- New hope for the bewildered: Intro Puzzles updated.
- Secrets of the Wet Lab: Foldit design update - Part 1 and Foldit design update - Part 2 for the latest results of testing proteins designed by Foldit players.
- As seen on TV: Origami Revolution. Nova on PBS featured protein folding, David Baker, Rosetta@Home and Foldit. (See minutes 20 through 28, with Foldit briefly mentioned at around 23:45.) YouTube also has Origami Revolution.
- FolditatUW - foldit's official YouTube channel.
- P1 - Introduction to Protein Design (15m)
- P2 - Design of New Protein Functions (27m)
- Beta_Helix's Foldit video the basics explained (40m)
- Through the eyes of a scientist Design solutions reviewed (26m)
- Design solutions reviewed Part 2 (22m)
The intro puzzles show you the tools, try them before trying a science puzzle.
Further help getting started:
- Foldit 101 - Useful information about Puzzle Types, the Cookbook and recipe basics.
- How to get started - With pictures from an actual puzzle
- Puzzle Results - screen shots of top scoring and interesting player solutions.
- Blackbelt Folding - Sessions 1,2, 3 & 4 denovo
- Electron Density - info and videos
- Hydrogen Bond Networks
- Download-Install-Troubleshoot includes Tracks, devprev and using multiple clients on Windows, Mac and Linux
- Foldit chat (IRC)
- Frequently asked questions
- Foldit Accessibility
- Foldit Translations
- Strategy - how to improve your score
- TheGame - tools, score details and Lua scripting
- Groups-Players - groups (teams), players and a bit of humour.
- The Research Room - advanced discussions and lots of external links
- Scientist and Developer Chats
- Hydrogen Bond Networks
- Drug Design Puzzles
- Interesting Articles
Contents ( View All Pages - Foldit Wikia Index )
These pages describe the science of protein folding.
- Primary Structure
- Secondary Structure
- Hydrophilic and Hydrophobic (also known as "blue out, orange in")
- Protein Folding Theory
- Biochemistry I
This is a wiki about the Foldit game that anyone can edit. Before you do edit it, however, please take a look around and determine whether or not the article you'd like to write already exists. (If it does exist, feel free to make it better!)
To write a new article, just enter the article title in the box below.
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- Talk and more...
- Check out the community portal to see what the community is working on, to give feedback or just to say hi.