Foldit is an online game in which humans try to solve one of the hardest computational problems in biology: protein folding. You don't need to know anything about biology to play the game, although a little background will help. Most Foldit player are not biologists. Read about The Science Behind Foldit.
Visit the fold.it, the official Foldit site to download the game and get started. Foldit runs on Windows, Mac, and 64-bit Linux. Use the feedback page if you're having trouble getting the game installed.
- Begin the begin: new Beginner Puzzles page added, six existing beginner puzzle pages updated.
- Not dead yet: Mozak and Zoran Popović featured in the New York Times. Foldit gets a mention way down in the article, in the past tense, as "attracting nearly a million players over its lifetime". Funeral arrangements pending.
- Mother liquor: Protein Crystallization explained, to along with design updates Part 1 and Part 2.
- Lua luau: the Lua scripting tutorials Beginner 1 through Beginner 5 have been updated and expanded.
- New hope for the bewildered: Intro Puzzles updated.
- As seen on TV: Origami Revolution. Nova on PBS featured protein folding, David Baker, Rosetta@Home and Foldit. (Minutes 20 through 28, with Foldit briefly mentioned at 23:45.)
- Oldie but goodie: 2013 animated video featuring the Contender's mimi and Renton Innes.
- FolditatUW - foldit's official YouTube channel.
- P1 - Introduction to Protein Design (15m)
- P2 - Design of New Protein Functions (27m)
- Beta_Helix's Foldit video the basics explained (40m)
- Through the eyes of a scientist Design solutions reviewed (26m)
- Design solutions reviewed Part 2 (22m)
Tools, tips, techniques
- Foldit 101 - Useful information about Puzzle Types, the Cookbook and recipe basics.
- How to get started - With pictures from an actual puzzle
- Puzzle Results - screen shots of top scoring and interesting player solutions.
- Blackbelt Folding - Sessions 1,2, 3 & 4 denovo
- Electron Density - info and videos
- Hydrogen Bond Networks
- Download-Install-Troubleshoot includes Tracks, devprev and using multiple clients on Windows, Mac and Linux
- Foldit chat (IRC)
- Frequently asked questions
- Foldit Accessibility
- Foldit Translations
- Strategy - how to improve your score
- TheGame - tools, score details and Lua scripting
- Groups-Players - groups (teams), players and a bit of humour.
- The Research Room - advanced discussions and lots of external links
- Scientist and Developer Chats
- Hydrogen Bond Networks
- Drug Design Puzzles
- Interesting Articles
Contents ( View All Pages - Foldit Wikia Index )
These pages describe the science of protein folding.
- Primary Structure
- Secondary Structure
- Hydrophilic and Hydrophobic (also known as "blue out, orange in")
- Protein Folding Theory
- Biochemistry I
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