Disulfide Bridge

From FoldIt Wiki

A disulfide bridge is formed when a sulfur atom from one Cysteine forms a single covalent bond with a sulfur atom from a second Cystine in a different part of the protein. This bond is termed a Disulfide Bridge; these bridges help to stabilize proteins, especially those secreted from cells. The presence of a pair of Cysteines in a protein indicates the possibility (but not the requirement) of a disulfide bridge.

Unlike a Hydrogen Bond, a disulfide bridge is not shown in the current implementation of FoldIt. Thus it cannot be said with certainty whether any given fold exhibits a disulfide bridge. Manipulating Cysteine sidechains so that their ends point toward one another has sometimes been noticed to yield points, but as it turns out, the developers have confirmed that this effect is unrelated to the disulfide bridge. As of the current implementation, disulfide bridges do not seem to be scored in FoldIt.

More information can be found at http://en.wikipedia.org/wiki/Disulphide_bridge